Our projects

Protecting the potency of a key tuberculosis drugThe TASP project is evaluating new approaches to extend the lifespan of the critical tuberculosis drug, bedaquiline, by improving detection...

Detecting tuberculosis in stool samplesThe STOOL4TB project has been awarded Global Health EDCTP3 funding to complete its EDCTP2-funded study of TB detection in children and people living...

Integrated control of multiple parasitic worm infectionsThe 3SI-CONTROL project is assessing whether it is safe and effective to administer multiple antiparasitic drugs simultaneously and...

Improving treatment of TB meningitisWith Global Health EDCTP3 funding, the EDCTP2-funded INTENSE-TBM project is completing a trial that could radically improve the treatment of tuberculosis...

A platform for evaluating Lassa fever treatmentsThe INTEGRATE project is creating a clinical trial platform able to support efficacy studies on multiple Lassa fever therapeutics.

Enhancing genomic surveillance in the Great Lakes regionThe GREAT-LIFE project is building a genomics-based infrastructure to track existing and new infectious disease threats and...

Improving tuberculosis detection outside the lungsThe EpiTB project is assessing the clinical impact of a new diagnostic device that is better able to detect TB infections outside the lung.

Building ‘One Health’ surveillance capacityThe PHM Hub project is strengthening epidemiology and disease-modelling capacity in West and Central Africa, with a particular focus on the human...

Mitigating the risk of antimalarial resistanceThe MARC-SE Africa project is enabling key countries in Africa to track and respond to rising rates of resistance to antimalarial drugs.

Community-based care for vulnerable children after hospital dischargeThe SDx project is assessing whether digital tools can enable community health workers to maintain contact with...

An adaptive trial platform for testing neonatal sepsis treatmentsThe SNIP-AFRICA project is establishing a research platform with an innovative trial design that will enable multiple...

Speeding up the diagnosis of tuberculosis meningitisThe PRECISE-TBM project aims to accelerate the detection of tuberculous meningitis, the deadliest form of TB that is a particular threat...

Amplifying access to new antibioticsThe ComBac-Africa project is working to improve access to new antibiotics in sub-Saharan Africa, incorporating measures to ensure their judicious use and...

Treating epilepsy caused by parasite infection  The NeuroSolve project is evaluating a new treatment for patients who develop epileptic seizures when tapeworm larvae become lodged in their...

Reaching those missing out on vaccinationThe REACH-OUT project is developing strategies to ensure that more ‘zero-dose’ children – those missing out entirely on the benefits of vaccines –...

Supporting mpox responses and research in eastern DRCThe MBOTE-SK project is embedding research within the response to the new clade Ib mpox outbreak in eastern DRC.

Detecting TB in childrenThe OPTIC-TB project is assessing whether the use of WHO-recommended clinician guidance (treatment-decision algorithms, TDAs) can improve the detection of...

Building research oversight capacity in Côte d’IvoireThe CECABI II project is developing the capacity of research ethics bodies in Côte d’Ivoire and enhancing coordination with its national...

Building regulatory capacity in West AfricaThe ECOWAS-RegECs project is helping to build regulatory and ethics capacity by simulating scientific advice and review of Lassa fever vaccine...