Our projects

Rapid protection against Ebola virusThe EBO-PEP project is evaluating whether monoclonal antibodies can protect close contacts of people with Ebola virus infections.

An enhanced EDCTP presence in AfricaA two-year renewal of funding to the EDCTP Africa Office is enabling it to support and coordinate Global Health EDCTP3 funded capacity-building...

Reducing cervical cancer by boosting HPV vaccination The IMPROVE-HPV project is exploring ways to improve take-up of vaccines against human papillomavirus (HPV), the main cause of cervical...

Understanding the spread of the newly emerged clade Ib mpox variantThe JUA-KIVU project is generating a clearer picture of the origins and spread of the novel strain of mpox virus (clade Ib)...

Enhancing treatment of parasitic worm infectionsThe eWHORM project is using an innovative trial design to assess the efficacy of a promising new therapeutic, oxfendazole, against multiple...

Once-weekly pills for HIV controlThe POA project is evaluating a radically simplified HIV treatment regimen that could make it much easier for people living with HIV to control viral...

New options for drug-resistant tuberculosisThe EX-DR TB project is aiming to preserve the potency of a key TB drug, bedaquiline, and advance the development of potential successors.

An overarching clinical trials network for AfricaThe CTCAN project is creating an umbrella network connecting existing clinical trial networks in sub-Saharan Africa to provide a...

Finding and treating Cryptosporidium parasite infectionsThe CryptoT&T project is developing a test to detect Cryptosporidium intestinal parasite infections, which could usher in targeted...

Screen and treat for human African trypanosomiasisThe STROGHAT project will determine whether a new drug, acoziborole, can be used in a ‘screen-and-treat’ approach for control of human...

A promising new antimalarialThe CUREMAL project is advancing a new antimalarial drug that could provide a much-needed alternative to artemisinin-based agents, to which malaria parasites are...

Improving detection and control of Ebola outbreaksThe Ebola PREP-TBOX project is developing a suite of tools to improve detection, treatment and public health responses to Sudan ebolavirus...

Boosting malaria vaccine potencyThe MVC-2G project is advancing a second-generation malaria vaccine targeting an additional stage in the malaria parasite life cycle.

Strengthening national ethics review systems in East AfricaThe SECRET project addresses a critical gap in Africa's clinical research ecosystem: the limited capacity of national research...

Advancing the development and future access of a new tuberculosis vaccineThe MTBVAC-AVANTE consortium, led by Biofabri, is advancing one of the world's most advanced tuberculosis vaccine...

Preventing transmission of viral infections during pregnancyThe MAGFA project is developing a point-of-care test to simultaneously detect HIV, syphilis and hepatitis B virus infections in...

Targeting malaria parasites within mosquitoesThe DEFEND project is piloting a highly innovative strategy to disrupt the spread of malaria by infecting mosquitoes with a strain of bacterium...

Gathering additional data on mpox vaccine in infants and pregnant women The PregInPoxVac project is generating data on the use of the MVA-BN vaccine to prevent mpox infections in pregnant...

Malaria treatment in early pregnancyThe SAFIRE project is establishing an innovative adaptive clinical trial platform to evaluate antimalarial treatments for women in the first trimester of...