Our projects

Targeting malaria parasites within mosquitoesThe DEFEND project is piloting a highly innovative strategy to disrupt the spread of malaria by infecting mosquitoes with a strain of bacterium...

Gathering additional data on mpox vaccine in infants and pregnant women The PregInPoxVac project is generating data on the use of the MVA-BN vaccine to prevent mpox infections in pregnant...

Malaria treatment in early pregnancyThe SAFIRE project is establishing an innovative adaptive clinical trial platform to evaluate antimalarial treatments for women in the first trimester of...

Improving treatment of diarrhoeal disease in malnourished children The TARGET project is assessing whether antibiotic treatments can reduce deaths and hospitalisations for young children...

Boosting clinical trial expertiseThe CREATIVE project is developing a cohort of early-career researchers with theoretical and hands-on experience in clinical trials across academic and...

Combining vaccination and drug-based prevention of malariaThe IMVACS project is assessing whether delivering malaria vaccines as part of seasonal malaria chemoprevention campaigns will...

Training new African ‘bioentrepreneurs’The SAHRI Fellowship project provides promising researchers from sub-Saharan Africa with a structured three-year training programme that includes a 6...

Using genomics to track mpox Building on the existing Global Health EDCTP3-funded ODIN project, the ODIN-Mpox project is applying genomic technologies to wastewater surveillance to track the...

Probiotics to boost rotavirus vaccine responsesThe PRoRota project is assessing whether probiotic supplements can boost responses to rotavirus vaccination and reduce the risk of diarrhoeal...

Rapid detection of Ebola virus infectionsThe EPoCA project is developing an innovative new point-of-care test for Ebola virus infections that will also give insights into infection severity...

Building research capacity in antimicrobial resistanceThe CATCR project is training a new generation of researchers in the increasingly critical field of antimicrobial resistance.

Boosting clinical research in East Africa The EACCR4 project is strengthening clinical research capacity across a wide range of sites in East Africa. 

Screening for tuberculosis using lung ultrasoundThe CAD LUS4TB project is assessing whether point-of-care ultrasound can be used in tuberculosis triage, ensuring that patients with the...

Coordinated strengthening of ethics review and regulatory capacity The SCALE-IT project is using a coordinated approach to strengthen ethics review and regulatory capacity across multiple...

Strengthening research capacity in Portuguese-speaking countriesThe CT-Luso project is developing ethical review and regulatory capacity specifically in Portuguese-speaking countries in sub...

Enhancing treatment of parasitic worm infectionsThe eWHORM project is using an innovative trial design to assess the efficacy of a promising new therapeutic, oxfendazole, against multiple...

Once-weekly pills for HIV controlThe POA project is evaluating a radically simplified HIV treatment regimen that could make it much easier for people living with HIV to control viral...

New options for drug-resistant tuberculosisThe EX-DR TB project is aiming to preserve the potency of a key TB drug, bedaquiline, and advance the development of potential successors.

An overarching clinical trials network for AfricaThe CTCAN project is creating an umbrella network connecting existing clinical trial networks in sub-Saharan Africa to provide a...

Finding and treating Cryptosporidium parasite infectionsThe CryptoT&T project is developing a test to detect Cryptosporidium intestinal parasite infections, which could usher in targeted...