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Background: Monkeypox virus (MPV) is a member of the Poxviridae family that includes smallpox, cowpox and chickenpox viruses. Endemic to equatorial Africa following casual human to animal or...

Detecting tuberculosis in stool samplesThe STOOL4TB project has been awarded Global Health EDCTP3 funding to complete its EDCTP2-funded study of TB detection in children and people living...

Integrated control of multiple parasitic worm infectionsThe 3SI-CONTROL project is assessing whether it is safe and effective to administer multiple antiparasitic drugs simultaneously and...

Improving treatment of TB meningitisWith Global Health EDCTP3 funding, the EDCTP2-funded INTENSE-TBM project is completing a trial that could radically improve the treatment of tuberculosis...

A platform for evaluating Lassa fever treatmentsThe INTEGRATE project is creating a clinical trial platform able to support efficacy studies on multiple Lassa fever therapeutics.

Enhancing genomic surveillance in the Great Lakes regionThe GREAT-LIFE project is building a genomics-based infrastructure to track existing and new infectious disease threats and...

Understanding mpox virus infectionsThe MOVIE-TRACE project is clarifying two key aspects of mpox infections: the speed at which the virus is cleared from the body and its infectiousness.

Field-testing moxidectin for river blindness controlThe EMINENCE project is exploring whether a newly developed drug, moxidectin, could accelerate the elimination of onchocerciasis (river...

Advancing monoclonal antibodies to treat HIV in infantsThe ENABLE project is assessing whether broadly neutralising antibodies could make the HIV virus undetectable in young infants.

Our overall objective is to integrate our consortium’s individual skills, capacity and innovations into advanced, low-cost and deployable digital dashboards and diagnostics to understand how...

Standardised tracking of malaria and tuberculosis drug resistance The PANGenS project will introduce standardised approaches for identifying malaria and TB genetic variants associated with...

The current Mpox outbreak affecting the Democratic Republic of the Congo, ongoing since 2023, has resulted in more than 19,000 causes and over 1,000 deaths, with women accounting for more...

Extending ivermectin use to young childrenThe IVM-KIDS project is developing a child-friendly formulation of ivermectin to ensure young children can benefit from this key drug for parasite...

Improving tuberculosis detection outside the lungsThe EpiTB project is assessing the clinical impact of a new diagnostic device that is better able to detect TB infections outside the lung.

Promoting use of malaria prevention after hospital discharge in childrenThe PDMC Saves Lives project is helping countries identify the best way to introduce a life-saving new approach to...

Disrupting mosquito feeding to prevent malariaThe LASR project is testing whether a newly developed mosquito repellent can reduce the community burden of malaria infections.

Supporting women living with HIV after pregnancyThe DOLPHIN-3 project is assessing whether it is feasible to temporarily transfer women living with HIV from oral antiretroviral therapy (ART)...

Pregnant women have an increased risk of severe mpox disease, however, the underlying mechanisms remain elusive. To better understand altered transmission pattern of MPXV and its impact on...

Optimising HIV treatments for pregnant womenGlobal Health EDCTP3 funding will enable the EDCTP2-supported PREGART project to complete a key trial that will provide evidence on the optimal...

Improving pneumonia treatment in young childrenThe OPT-bCPAP project is supporting the rollout of an innovative low-cost approach with the potential to prevent the deaths of thousands of...