Our projects

Improving HIV prevention in mobile populationsThe MOBILE MEN project aims to identify the preferred HIV prevention option for men who migrate for work, as well as the key health system...

Preventing dengue feverThe DENSTAR project is testing a vaccine that could address the growing challenge posed by the dengue virus in sub-Saharan Africa.

Coordinated development of regulatory systems in Southern AfricaThe SEARCH II project is strengthening and harmonising regulatory structures in Southern and Eastern African countries.

Enhancing artificial intelligence detection of tuberculosisThe AddiCAD project is advancing a new digital tool that combines AI analysis of chest X-rays with protein biomarker data to...

Building ethics review and regulatory capacity in East AfricaThe ACCESSAFRICA2 project is strengthening ethics review and regulatory capacity in Ethiopia and Uganda.

Establishing a research integrity frameworkThe SERCEA project aims to strengthen mechanisms that promote and ensure the integrity of scientific research in East Africa.

Preventing chikungunya infectionsThe ACT-CHIK project is advancing a new vaccine against the chikungunya virus to address its growing burden on African populations and health systems.

Simplifying treatment of neglected skin diseasesThe TEBULA project is advancing a potentially revolutionary new treatment for two neglected mycobacterial diseases: leprosy and Buruli ulcer.

Widening genomic surveillance in Southern and Eastern AfricaThe GenPath Africa project is expanding existing genomic surveillance infrastructure to capture information on drug-resistant...

Advancing malaria treatments for pregnant womenAdditional Global Health EDCTP3 funding is completing the evaluation of a new antimalarial treatment for pregnant women.

Preventing the return of tuberculosis The RECENT-TB project is exploring whether a course of preventive antibiotics after TB treatment can prevent disease recurrence and how to target those...

Targeting malaria parasites within mosquitoesThe DEFEND project is piloting a highly innovative strategy to disrupt the spread of malaria by infecting mosquitoes with a strain of bacterium...

Gathering additional data on mpox vaccine in infants and pregnant women The PregInPoxVac project is generating data on the use of the MVA-BN vaccine to prevent mpox infections in pregnant...

Malaria treatment in early pregnancyThe SAFIRE project is establishing an innovative adaptive clinical trial platform to evaluate antimalarial treatments for women in the first trimester of...

BACKGROUND: Diarrhoea is an important cause of morbidity and mortality in children under 5, especially in SSA. WHO guidelines do not recommend antibiotics for acute watery diarrhoea, while...

Building genomic surveillance capacity in EthiopiaThe EpiGen Ethiopia project is bringing together multiple partners to strengthen the country’s capacity to detect and track known and...

Preventing diabetes in people living with HIVWith Global Health EDCTP3 funding, the META Trial project will be able to complete its landmark EDCTP2-funded trial of metformin for diabetes...

Tackling severe malaria in remote locationsThe SEMA ReACT study will determine whether children with severe malaria can be treated entirely in the community, when transportation to health...

Accelerating young people’s access to antiretroviralsThe CHAPAS-5 project is establishing a flexible clinical trial platform that will accelerate the evaluation of antiretroviral treatments...