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Protecting the potency of a key tuberculosis drugThe TASP project is evaluating new approaches to extend the lifespan of the critical tuberculosis drug, bedaquiline, by improving detection...
Treating epilepsy caused by parasite infection The NeuroSolve project is evaluating a new treatment for patients who develop epileptic seizures when tapeworm larvae become lodged in their...
Reaching those missing out on vaccinationThe REACH-OUT project is developing strategies to ensure that more ‘zero-dose’ children – those missing out entirely on the benefits of vaccines –...
Supporting mpox responses and research in eastern DRCThe MBOTE-SK project is embedding research within the response to the new clade Ib mpox outbreak in eastern DRC.
Detecting TB in childrenThe OPTIC-TB project is assessing whether the use of WHO-recommended clinician guidance (treatment-decision algorithms, TDAs) can improve the detection of...
Building research oversight capacity in Côte d’IvoireThe CECABI II project is developing the capacity of research ethics bodies in Côte d’Ivoire and enhancing coordination with its national...
Improving treatment of cutaneous leishmaniasisThe MAMS4CL project is establishing a clinical trial platform to test improved treatments for cutaneous leishmaniasis, a parasitic disease that...
Factors affecting susceptibility to and severity of mpoxThe DECIPHER-MPOX project is identifying host- and virus-related factors responsible for susceptibility to and the severity of mpox...
Detecting tuberculosis in stool samplesThe STOOL4TB project has been awarded Global Health EDCTP3 funding to complete its EDCTP2-funded study of TB detection in children and people living...
Integrated control of multiple parasitic worm infectionsThe 3SI-CONTROL project is assessing whether it is safe and effective to administer multiple antiparasitic drugs simultaneously and...
Improving treatment of TB meningitisWith Global Health EDCTP3 funding, the EDCTP2-funded INTENSE-TBM project is completing a trial that could radically improve the treatment of tuberculosis...
A platform for evaluating Lassa fever treatmentsThe INTEGRATE project is creating a clinical trial platform able to support efficacy studies on multiple Lassa fever therapeutics.
Protecting antibiotic potencyThe ASPIRE project is assessing whether improved infection prevention and control, coupled with more personalised antibiotic use, can reduce pressures driving...
Targeting vectors for infection prediction and controlThe IMPACTING project is collecting data on a host of insect vectors that spread infections to help better predict the risk of...
Rapid testing of urinary tract infectionsThe UTI-Diag project is exploring whether point-of-care tests could improve detection and management of urinary tract infections (UTIs) and reduce...
Stratifying care of hospitalised childrenThe PediSEP1 project is testing an approach to identify low-risk children who can be safely discharged from the hospital, allowing clinical attention...
Advancing test-and-treat strategies for vivax malariaThe PvSeroRDT project is exploring whether a new diagnostic test for Plasmodium vivax could underpin a test-and-treat strategy for this...
Infectious diseases such as COVID-19 and Ebola are leading contributors to the high morbidity and mortality in sub-Saharan African (SSA), yet these countries have inadequate capacity to...
Enhancing genomic surveillance in the Great Lakes regionThe GREAT-LIFE project is building a genomics-based infrastructure to track existing and new infectious disease threats and...
Improving tuberculosis detection outside the lungsThe EpiTB project is assessing the clinical impact of a new diagnostic device that is better able to detect TB infections outside the lung.