Our projects

Understanding mpox virus infectionsThe MOVIE-TRACE project is clarifying two key aspects of mpox infections: the speed at which the virus is cleared from the body and its infectiousness.

Antibiotic-based combination therapy for severe malaria and bacterial bloodstream infectionsThe FACT project is developing an innovative treatment that targets both severe malaria and...

Field-testing moxidectin for river blindness controlThe EMINENCE project is exploring whether a newly developed drug, moxidectin, could accelerate the elimination of onchocerciasis (river...

Advancing monoclonal antibodies to treat HIV in infantsThe ENABLE project is assessing whether broadly neutralising antibodies could make the HIV virus undetectable in young infants.

Automating parasite egg detectionThe DIDIDI project is developing automated systems and AI tools to provide a more rapid assessment of parasitic worm burdens.

Standardised tracking of malaria and tuberculosis drug resistance The PANGenS project will introduce standardised approaches for identifying malaria and TB genetic variants associated with...

Improving treatment of TB meningitisWith Global Health EDCTP3 funding, the EDCTP2-funded INTENSE-TBM project is completing a trial that could radically improve the treatment of tuberculosis...

A platform for evaluating Lassa fever treatmentsThe INTEGRATE project is creating a clinical trial platform able to support efficacy studies on multiple Lassa fever therapeutics.

Enhancing genomic surveillance in the Great Lakes regionThe GREAT-LIFE project is building a genomics-based infrastructure to track existing and new infectious disease threats and...

Improving tuberculosis detection outside the lungsThe EpiTB project is assessing the clinical impact of a new diagnostic device that is better able to detect TB infections outside the lung.

AI-informed treatment of diarrhoeal diseaseThe CARE-AFRICA project is developing an innovative AI-based tool to guide diagnostics and treatment of diarrhoeal diseases in children under 5 in...

Promoting use of malaria prevention after hospital discharge in childrenThe PDMC Saves Lives project is helping countries identify the best way to introduce a life-saving new approach to...

Widening genomic surveillance in Southern and Eastern AfricaThe GenPath Africa project is expanding existing genomic surveillance infrastructure to capture information on drug-resistant...

Advancing malaria treatments for pregnant womenAdditional Global Health EDCTP3 funding is completing the evaluation of a new antimalarial treatment for pregnant women.

Preventing the return of tuberculosis The RECENT-TB project is exploring whether a course of preventive antibiotics after TB treatment can prevent disease recurrence and how to target those...

Building ‘One Health’ surveillance capacityThe PHM Hub project is strengthening epidemiology and disease-modelling capacity in West and Central Africa, with a particular focus on the human...

Mitigating the risk of antimalarial resistanceThe MARC-SE Africa project is enabling key countries in Africa to track and respond to rising rates of resistance to antimalarial drugs.

Community-based care for vulnerable children after hospital dischargeThe SDx project is assessing whether digital tools can enable community health workers to maintain contact with...

An adaptive trial platform for testing neonatal sepsis treatmentsThe SNIP-AFRICA project is establishing a research platform with an innovative trial design that will enable multiple...