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Disrupting mosquito feeding to prevent malariaThe LASR project is testing whether a newly developed mosquito repellent can reduce the community burden of malaria infections.

Detecting TB in childrenThe OPTIC-TB project is assessing whether the use of WHO-recommended clinician guidance (treatment-decision algorithms, TDAs) can improve the detection of...

Building capacity for HIV research in childrenThe SUPPORT project is leveraging two EDCTP2-funded HIV projects to provide a career development platform for African researchers.

Optimising HIV treatments for pregnant womenGlobal Health EDCTP3 funding will enable the EDCTP2-supported PREGART project to complete a key trial that will provide evidence on the optimal...

Improving pneumonia treatment in young childrenThe OPT-bCPAP project is supporting the rollout of an innovative low-cost approach with the potential to prevent the deaths of thousands of...

Improving care of female genital schistosomiasisThe WINGS-4-FGS project is carrying out multiple activities to raise awareness, enhance detection and improve treatment of female genital...

The overall goal of this project is to provide scientific evidence for WHO policymaking on the longterm efficacy, safety, acceptability and cost-effectiveness of using R21/Matrix-Malaria...

Pregnant women have an increased risk of severe mpox disease, however, the underlying mechanisms remain elusive. To better understand altered transmission pattern of MPXV and its impact on...

The 2nd Generation Malaria Vaccine Consortium (MVC-2G) will build on the programmatic use of the first-generation Plasmodium falciparum vaccine, R21 with Matrix-M™, and accelerate the...

Why RER-CTO?: The conduct of clinical trials requires competent ethics committee and regulatory authorities that can review clinical trial applications and monitor processes independently...

Field-testing moxidectin for river blindness controlThe EMINENCE project is exploring whether a newly developed drug, moxidectin, could accelerate the elimination of onchocerciasis (river...

Understanding mpox virus infectionsThe MOVIE-TRACE project is clarifying two key aspects of mpox infections: the speed at which the virus is cleared from the body and its infectiousness.

Advancing monoclonal antibodies to treat HIV in infantsThe ENABLE project is assessing whether broadly neutralising antibodies could make the HIV virus undetectable in young infants.

Integrated control of multiple parasitic worm infectionsThe 3SI-CONTROL project is assessing whether it is safe and effective to administer multiple antiparasitic drugs simultaneously and...

Stratifying care of hospitalised childrenThe PediSEP1 project is testing an approach to identify low-risk children who can be safely discharged from the hospital, allowing clinical attention...

Advancing test-and-treat strategies for vivax malariaThe PvSeroRDT project is exploring whether a new diagnostic test for Plasmodium vivax could underpin a test-and-treat strategy for this...

Detecting tuberculosis in stool samplesThe STOOL4TB project has been awarded Global Health EDCTP3 funding to complete its EDCTP2-funded study of TB detection in children and people living...

Improving treatment of TB meningitisWith Global Health EDCTP3 funding, the EDCTP2-funded INTENSE-TBM project is completing a trial that could radically improve the treatment of tuberculosis...

Promoting use of malaria prevention after hospital discharge in childrenThe PDMC Saves Lives project is helping countries identify the best way to introduce a life-saving new approach to...

Safety monitoring during pregnancyThe PROTECT project is creating a network of sites in East Africa to monitor the safety of vaccines administered during pregnancy.