Our projects

Establishing a research integrity frameworkThe SERCEA project aims to strengthen mechanisms that promote and ensure the integrity of scientific research in East Africa.

Preventing chikungunya infectionsThe ACT-CHIK project is advancing a new vaccine against the chikungunya virus to address its growing burden on African populations and health systems.

Simplifying treatment of neglected skin diseasesThe TEBULA project is advancing a potentially revolutionary new treatment for two neglected mycobacterial diseases: leprosy and Buruli ulcer.

Widening genomic surveillance in Southern and Eastern AfricaThe GenPath Africa project is expanding existing genomic surveillance infrastructure to capture information on drug-resistant...

Advancing malaria treatments for pregnant womenAdditional Global Health EDCTP3 funding is completing the evaluation of a new antimalarial treatment for pregnant women.

Preventing the return of tuberculosis The RECENT-TB project is exploring whether a course of preventive antibiotics after TB treatment can prevent disease recurrence and how to target those...

Treating epilepsy caused by parasite infection  The NeuroSolve project is evaluating a new treatment for patients who develop epileptic seizures when tapeworm larvae become lodged in their...

Reaching those missing out on vaccinationThe REACH-OUT project is developing strategies to ensure that more ‘zero-dose’ children – those missing out entirely on the benefits of vaccines –...

Supporting mpox responses and research in eastern DRCThe MBOTE-SK project is embedding research within the response to the new clade Ib mpox outbreak in eastern DRC.

Detecting TB in childrenThe OPTIC-TB project is assessing whether the use of WHO-recommended clinician guidance (treatment-decision algorithms, TDAs) can improve the detection of...

Building research oversight capacity in Côte d’IvoireThe CECABI II project is developing the capacity of research ethics bodies in Côte d’Ivoire and enhancing coordination with its national...

Building regulatory capacity in West AfricaThe ECOWAS-RegECs project is helping to build regulatory and ethics capacity by simulating scientific advice and review of Lassa fever vaccine...

Strengthening clinical trial oversight in East AfricaThe RER-CTO project is strengthening clinical trial oversight capacity and harmonising regulatory processes in Ethiopia and Tanzania.

Safety monitoring during pregnancyThe PROTECT project is creating a network of sites in East Africa to monitor the safety of vaccines administered during pregnancy.

Improving tuberculosis detection in childrenThe Decide-TB project is evaluating tools that could help clinicians diagnose TB more reliably in children.

Enhancing uptake of tuberculosis preventive treatmentThe TEST4TPT project seeks to facilitate uptake of TB preventive treatment by enhancing early detection of exposure to TB bacteria.

Closing the diagnostic gap for paediatric tuberculosisThe ACT4KIDS-TB project is assessing whether combining different data sources can enable a clinic-decision-making app that supports...

Extending malaria treatment options for young childrenThe ASAQ-PAC project is developing a child-friendly version of a key antimalarial combination to enable malaria control programmes to...

Protecting the potency of a key tuberculosis drugThe TASP project is evaluating new approaches to extend the lifespan of the critical tuberculosis drug, bedaquiline, by improving detection...