20+ years of results

EDCTP programmes contributed to developing and implementing new or improved medical interventions

First ever malaria vaccines
RTS,S (only one with the European Medicines Agency's positive opinion)
AS01 and R21
Matrix-M RTS,S
AS01 plus seasonal malaria chemoprevention (SMC)
The Lancet, Volume 397, Issue 10287, P1809-1818, May 15, 2021
Combination treatment for parasitic worm infections
(soil-transmitted helminths)
Albendazole and Ivermectin
The Lancet Infectious Diseases, Vol. 25, P548-559, Issue 5, May 2025
First paediatric formulation for treating multiple episodes of malaria
Pyramax®
The Lancet Infectious Diseases, Volume 16, Issue 2, P189-198, February 2016
New treatment option for schistosomiasis in young children
Arpraziquantel
The Lancet Infectious Diseases, Vol. 23, Issue 7, P867-876, July 2023
First oral treatment of an acute form of sleeping sickness
(Trypanosoma brucei (T.b.) rhodesiense)
Fexinidazole Winthrop
The Lancet Global Health, Volume 13, Issue 5, e910-e919, May 2025
Simplified treatment of HIV-associated cryptococcal meningitis
Single high-dose amphotericin B
NEJM, Volume 386, NO. 12, P1109-1120, March 2022
Combination treatment for uncomplicated malaria in children
Dihydroartemsinin plus Piperaquine (DHAPQ)
PLOS Medicine, 8(11): e1001119, November 8, 2011
First paediatric formulation for treating HIV-infected children
Triomune Baby/Junior
AIDS 22(5): p 557-565, March 12, 2008

And launched two emergency calls to respond to the Ebola outbreak (2018) and the COVID-19 pandemic (2020).